In the current era of innovation in drug discovery, biotechnology, medical devices or natural products, a key factor in evaluation of a newly designed molecule or product is to obtain robust and quality data from optimally designed experiments.

We at TheraIndx endeavour to meet these criteria. TheraIndx offers wide range of animal disease models covering a variety of critical therapeutic areas such as infection & AMR, oncology, metabolic disorder, wound healing, dermatology, inflammation & pain & neurology. We actively consult with our partners in selection of appropriate models as well as establish and validate new models.

Animal Models of Infection


  • Complicated Urinary Tract Infection (cUTI)
  • Urinary Tract Infection
  • Thigh Infection in Neutropenic Mice with Gm +ve & Gm –ve Pathogens
  • Neutropenic Thigh Infection Model : Dose Fractionation to Identify PK/PD Index of Efficacy


  • Complicated Urinary Tract Infection (cUTI)
  • Urinary Tract Infection
  • Thigh Infection in Neutropenic & Non-Neutropenic Rat with Gm +ve & Gm –ve Pathogens
  • Neutropenic Rat Lung Infection Model with Epithelial Lining Fluid PK

Rabbit & Guinea Pig

  • Keratitis
  • Rhinosinusitis
  • Acute Otitis Media
  • Neutropenic Guinea Pig Model of Systemic Candidiasis

Animal Models of Metabolic Disorder

  • NASH Model in Rat
  • Adriamycin Induced Chronic Nephropathy (CKD) in Mice
  • Folic Acid induced Acute Kidney Injury (AKI) in Mice
  • Cisplatin Induced Acute Kidney Injury (AKI) in Mice
  • Genetic Models – Zucker Obese Rat (Zucker fa/fa), db/db Mice and Zucker Diabetic Fatty (ZDF)
  • Diet Induced - Obesity Using C57BL/6 Mice (DIO)
  • HFD/STZ (Low Dose) Induced Type 2 Diabetes in Rats
  • STZ Induced Diabetes Type1
  • STZ + Nicotinamide induced Diabetes Type 2
  • Carbon Tetrachloride (CCl4) Induced Liver Fibrosis in Mice
  • Ischemic Reperfusion Kidney Injury in Rat (IRI)
  • Triton Induced Hyperlipidemia
  • Cholesterol Induced Hypercholesterolemia
  • OGTT/IGTT Assay
  • Gentamycin Induced Nephro-toxicity
  • Sodium Oxalate Induced Urolithiasis
  • Osteoporosis Model in Rat

Animal Models of Dermatology

  • Alopecia Models (Testosterone, DHT) in Mice
  • Psoriasis Model in Mice
  • Atopic Dermatitis Model in Mice
  • Vitiligo Model in Guniea Pigs
  • Acne Model in Mice
  • Inflammation Model in Mice & Rat
  • Anti-wrinkle Activity in Mice

Animal Models of Auto Immune Disorder

  • Arthritis - Collagen induced Arthritis (CIA) (Rat & Mouse), Adjuvant Induced Arthritis (AIA) (Rat)
  • Imquiod Induced Psoriasis In Mice
  • Experimental Autoimmune Encephalomyelitis (EAE) in Mice
  • Colitis – Dextran Sulphate Sodium (DSS) Induced (Ulcerative Colitis, Mouse), Trinitrobenzene Sulphonate (TNBS) Induced (Crohn's Disease, Rat)
  • Hypersensitivity Type 1 - Ovalbumin Induced Dermatitis (Mouse), Oxazolone Induced Dermatitis (Mouse)

Animal Models of Wound Healing

  • Excision Wound Healing in Rat
  • Excision Wound Healing in Diabetic Induced Rat
  • Excision Wound Infection in Rat
  • Excision Diabetic Wound Infection in Rat
  • Burn Wound Healing in Rat
  • Burn Wound Infection

Animal Models of Inflammation & Pain

  • Carageenan Induce Paw Edema in Rat
  • LPS induced Pulmonary Inflammation (Rat)
  • Bleomycin Induced Pulmonary Fibrosis (Rat)
  • Oxazolone/ Xylene/ Arachidonic Acid/ Croton Oil Induced Ear Edema
  • Cotton Pellet Induced Granuloma
  • Chemically Induced Pain Model - Acetic Acid Induced Writhing (Rat), Formalin Induced Tonic Pain (Rat & Mouse)
  • Hot and Cold Plate Method.
  • Tail-Flick Test

Animal Models of Neurology

  • Epilepsy- Isoniazide (INH )Induced, Picrotoxin Induced, Maximum Electro Shock (MES) Induced Convulsion
  • Parkinsonism - MPTP Induced
  • Depression - Forced Swim Test, Tail Suspension Test
  • Antipsychotic - Inhibition of Amphetamine Stereotypy in Rats, Inhibition of Apomorphine Climbing in Mice
  • Nootropics - Morris Water Maze, T-Maze, Y-Maze
  • Anxiety - Elevated Plus Maze, Light-Dark Model, Open Field Test
  • Muscle Coordination - Rotarod Test, Grip Strength Test, Dexamethasone Induced Cachexia
  • Alzheimer’s Disease
  • LPS induced Neuro Inflammation

Animal Models of Ulcer

  • Pylorus Ligation in Rat
  • Indomethacin Induced Gastric Ulcer
  • Stress Induced Ulcer (Cold, Heat and Restraint Stress)
  • Ethanol - Induced Gastric Ulcer in Rat