In vitro ADMET

  • Solubility : Kinetic, Equilibrium
  • Plasma Protein Binding: Mouse, Rat, Dog, Human
  • Permeability : PAMPA, Caco2 (Unidirectional, Bidirectional)
  • Microsomal Metabolic Stability: Mouse, Rat, Dog, Human
  • Human CYP450 assays: Inhibition, Isoform Phenotyping
  • Cytotoxicity : HepG2, A549, MDCK cell lines
  • MET-ID