Drug Discovery services refer to the range of scientific and technological services aimed at facilitating the discovery and development of new drugs for various therapeutic areas or diseases, particularly in the context of structure-based drug discovery. The drug discovery process encompasses Target identification, involving the identification of potential drug targets like proteins or genes involved in disease processes, and validating their therapeutic potential. This is followed by Medicinal chemistry, ADME-ToX studies (Absorption, Distribution, Metabolism, Excretion, and Toxicity) to assess the behavior of the drug within the body and its potential adverse effects, Pharmacology studies to evaluate the efficacy, safety, and pharmacological properties, as well as Preclinical development and formulation development prior to clinical trials.Contact Us
TheraIndx offers stand-alone and fully integrated drug discovery services across the different stages of preclinical drug discovery from Hit Identification to lead Identification, Lead Optimization to Preclinical Development.
In Vitro Assays are an essential component of drug discovery and drug development services, as they provide valuable information about the potential efficacy and safety of the drug candidates before they are tested on animals. In Vitro assays are conducted in a controlled environment outside of living organisms, using cells, tissues, or isolated biomolecules to study the biological activity, mechanism of action, and effects of various substances such as drugs, chemicals, or compounds on specific targets or systems.
In Vitro ADME (Absorption, Distribution, Metabolism, and Excretion) studies are an essential part of structure-based drug discovery and development. These studies involve the use of In Vitro models and assays to assess the Pharmacokinetic properties of potential drug candidates before they are tested in animal models or humans. In Vitro ADME studies provide valuable information about a drug's absorption, distribution within the body, metabolism, and elimination, helping researchers make informed decisions about the drug's viability and potential dosing regimens.
In drug discovery services, Pharmacokinetic (PK) studies are an essential part of evaluating the behavior of a drug within an organism. PK studies In Vivo involve studying the absorption, distribution, metabolism, and excretion (ADME) of a drug candidate in animal models or human subjects. These studies provide valuable information about how the drug is processed by the body, its bioavailability, and its overall Pharmacokinetic profile.
In Vivo Pharmacology studies play a crucial role in drug discovery and drug development services. These studies involve the use of living organisms, such as animals, to evaluate the safety, efficacy, and pharmacokinetic properties of potential drug candidates before they are tested in humans.
Toxicology studies are conducted to evaluate the adverse effects of chemicals, substances, or physical agents on living organisms. These studies aim to understand the toxicity and potential risks associated with exposure to these agents, and they play a crucial role in assessing the safety of various products, such as pharmaceuticals, pesticides, food additives, and industrial chemicals.
At TheraIndx, we value research. At the heart of our business lies our strength in consulting. We understand the challenges faced by a drug discovery team. We, therefore, take utmost care to consult, hand hold suggest the best possible way to achieve optimal results. Some of our key strengths:
Extensive knowledge and experience in drug discovery
Capability to deliver projects of any size on time
Deliver high-quality preclinical candidate
Disorder, kidney injury, ulcer, and alopecia
Broad therapeutic area expertise including infection, oncology, metabolic disorder
Inflammation & Pain, Dermatology, Neurology, wound healing, autoimmune
Interpretation of biological data
Optimization of ADME, PK, and PK/PD profiles
Consulting approach - strategic importance to every client
Flexible approach based on client’s requirement
Project management expertise
Assured IP protection & data security