Accelerating Biologics with precision Analytical and Binding assays
Introduction:
Biologics are complex therapeutics that require rigorous and comprehensive characterisation to ensure their safety, efficacy and long-term benefits. Understanding the structural heterogeneity, binding properties and functional properties of the molecules are critical parameter for advancement of any complex biologics. The comprehensive characterisation involves identity, potency, bioactivity and mechanism of action using advanced analytical platforms such as ELISA, Western blotting, FACS, qPCR and various cell-based assays.
This characterisation is not a regulatory requirement but is the foundation and a critical step for finding successful clinical candidates and achieve long term therapeutics effects. At TheraIndx life sciences, we bring vastly experienced scientific depth with technical expertise to deliver every stage of biologics analysis.
TheraIndx role expertise
Our integrated validated assay solutions are designed to provide deep insights into structure, binding and expression pattern. Our assays can be custom designed to support every stage of your drug discovery to be ready for any future regulatory work.
Our core offerings
- ELISA and western blotting: Quantitative and qualitative protein analysis
- FACS-based binding assays: Detection of cell surface interactions, receptor engagement.
- qPCR: Measures gene expression and transcriptional changes
- FRET/ BRET assays: Real time insights into protein-protein interactions
- 3D organoid models: Human relevant system for evaluating biologics
Partnering for precision
From early drug discovery to IND-enabling studies, TheraIndx life sciences partners with pharmaceutical companies/ academic institutions to assist in advancing their molecule of interest with meaningful data.
“TheraIndx Partnering with innovators to drive biologics forward”
